Applications

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Case Studies in Osmolality

Bibliography

Osmometry:

An overview of Osmometry including several case studies and an evaluation of the importance of stat osmometry in modern-day diagnostic medical applications. Robert Dufour, M.D.) See complete article in the Osmolality section, General Information.

Case A - Possible Toxin Ingestion
A 43-year-old white male with a history of depression and alcohol abuse was found lethargic on the floor of his room by his family. He was brought to the emergency room, where he was found to be confused; he became comatose over the next hour.
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Case B - Evaluation of Hyponatremia
The supervisor in the stat laboratory noticed that the results on a patient in the operating room had changed significantly since the previous evening, as shown in the accompanying table.
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Case C - Evaluation of Hyponatremia
A 32-year-old male presented with a history of one episode of passing blood in his stool. He had a history of alcohol abuse, and had been in an automobile accident the previous year, injuring his head.
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Case D - Evaluation of Hyponatremia
The evening supervisor notes that a patient's serum sodium has failed delta check alerts compared to the results from the previous week. She had run the initial specimen on the Beckman CX-7, and repeated the test on the Ektachem.
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Case E - Evaluation of Hyponatremia
A 74-year-old man was admitted in February with a stroke. After about one month in the hospital, he developed shortness of breath and was found to have pneumonia, which was resistant to treatment, raising the possibility of an ongoing source.
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Case F - Evaluation of High Urine Output
A 54-year-old man is hospitalized on the psychiatry service for treatment of manic-depressive disorder; he is currently receiving lithium carbonate treatment. He states that he is always thirsty, and he has a daily urine output of over 8 liters per day.
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Case G - Evaluation of High Urine Output
A 36-year-old man with a history of alcohol abuse was admitted for evaluation of seizures. On the evening following admission, he fell, hitting his head. While the wound was being sutured, he became less responsive and lapsed into a coma.
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Case H - Evaluation of Decreased Urine Output
A 35-year-old man with a history of alcohol abuse was admitted with loss of appetite and diarrhea; he also had a diagnosis of cirrhosis. Treatment began with vancomycin because of a positive blood culture.
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Case I - Evaluation of Decreased Urine Output
A 74-year-old male with a history of insulin dependent diabetes, hypertension, and a "cardiac problem" suffered a perforated bowel in late January and underwent emergency surgery for repair; an ileostomy was created.
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