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Internal Medicine/Endocrinology Inappropriate ADH Syndrome: Serum and urine osmolality help determine whether SIADH is present in a patient with normal blood volume. ADH Therapy: Urine osmolality provides a rapid measure of patient response, assisting therapy modification. Diabetes Insipidus: Urine osmolality can measure the effects of humoral factors and offers rapid determination of the diseases etiology. Insulin therapy: Osmolality provides rapid assessment of the effectiveness of the insulin therapy. Differential diagnosis of polyuria: Osmolality
can help to differentiate between diabetes insipidus and psychogenic polyuria.
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